| Logiciel Nintendo DS | Date de sortie 2006 |
| Madden NFL 07 (EA) | août-06 |
| Disney's American Dragon : Jake Long (Disney/Buena Vista Games) | sept-06 |
| Brick’em all DS (Digital Bros) | sept-06 |
| LEGO Star Wars II : The Original Trilogy (Lucas Arts/Activision) | sept-06 |
| Bratz : Forever Diamondz (THQ) | sept-06 |
| Super Fruit Fall (System 3) | sept-06 |
| Tennis Masters (System 3) | sept-06 |
| Sudoku Mania (ZOO Digital) | 08-sept-06 |
| FIFA 07 (EA) | 29-sept-06 |
| 42 Jeux Indémodables (Nintendo) | 29-sept-06 |
| Hardcore Pool (ZOO Digital) | 29-sept-06 |
| Alexandra Ledermann (Ubisoft) | 3ème trimestre 2006 |
| Asphalt 2 Urban GT(Ubisoft) | 3ème trimestre 2006 |
| Catz (Ubisoft) | 3ème trimestre 2006 |
| Beetle King (Digital Bros) | oct-06 |
| Deep Labyrinth (Digital Bros) | oct-06 |
| Guru Guru Naget (Digital Bros) | oct-06 |
| Léa Passion Vétérinaire (dtp) | oct-06 |
| Disney's The Little Mermaid : Special Edition (Disney/Buena Vista Games) | oct-06 |
| Labyrinth (Digital Bros) | oct-06 |
| Biker Mice From Mars (Game Factory/K.E. Media) | oct-06 |
| Cartoon Network Racing (Game Factory/K.E. Media) | oct-06 |
| Disney's Chicken Little 2 : Ace in Action (Disney/Buena Vista Games) | oct-06 |
| Avatar : The Legend of Aang (THQ) | oct-06 |
| Ages of Empires II : Age of Kings (Majesco/THQ) | oct-06 |
| Dino Master (Majesco) | oct-06 |
| Contact (Marvelous/Rising Star Games) | oct-06 |
| New Zealand Story Revolution (Rising Star Games) | oct-06 |
| Y’s Strategy (Rising Star Games) | oct-06 |
| Spyro – The Legend (Vivendi) | oct-06 |
| Scooby Doo! Who's Watching Who? (THQ) | oct-06 |
| Crash Boom Bang (Vivendi) | oct-06 |
| Barnyard (THQ) | oct-06 / fév-07 |
| Navigateur Nintendo DS (Nintendo) | 06-oct-06 |
| English Training : Progressez en Anglais sans Stresser (Nintendo) | 13-oct-06 |
| Asterix & Obelix XXL 2 "Mission Wifix" (ATARI) | 13-oct-06 |
| Warlords Champion (D3P) | 13-oct-06 |
| Les Sims2 Animaux et Compagnie (EA) | 20-oct-06 |
| Charlotte aux Fraises (Game Factory/K.E. Media) | 20-oct-06 |
| Sudoku Master (Nintendo) | 27-oct-06 |
| Actionloop (Nintendo) | 27-oct-06 |
| Nintendo DS Lite Rose | 27-oct-06 |
| Lara Croft Tomb Raider : Legend (Eidos) | oct / nov-06 |
| Les Rebelles de la Forêt (Ubisoft) | oct / nov-06 |
| Superman Returns : The Videogame (EA) | Automne 2006 |
| BIONICLE HEROES (Eidos) | Automne 2006 |
| Death Jr. and The Science Fair of Doom (Konami) | Automne 2006 |
| Lunar Knights (Konami) | Automne 2006 |
| My Frogger Toy Trials (Konami) | Automne 2006 |
| Steel Horizon (titre provisoire) (Konami) | Automne 2006 |
| Winx Club : The Quest for the Codex (Konami) | Automne 2006 |
| Xiaolin Showdown (Konami) | Automne 2006 |
| Castlevania : Portrait of Ruin (Konami) | nov-06 |
| Monster Bomber (Digital Bros) | nov-06 |
| Monster Puzzle (Digital Bros) | nov-06 |
| Super Black Bass Fishing (Majesco) | nov-06 |
| Marvel : Ultimative Alliance (Activision) | nov-06 |
| Tony Hawk's Downhill Jam (Activision) | nov-06 |
| Disney’s Kim Possible Global Gemini (Disney/Buena Vista Games) | nov-06 / mars-07 |
| Cooking Mama (Digital Bros) | nov-06 |
| Need For Speed Carbon (EA) | nov-06 |
| Spongebob Squarepants and Friends : Creature from Krusty Krab (THQ) | nov-06 |
| Impossible Mission (System 3) | nov-06 |
| Mech Assault Phantom War (Majesco/THQ) | nov-06 |
| Super Nacho (Majesco/THQ) | nov-06 |
| Happy Feet (Midway) | nov-06 |
| Over The Hedge – Hammy Goes Nuts (Activision) | nov-06 |
| Spider-Man : Battle for New York (Activision) | nov-06 |
| Eragon (Vivendi) | nov-06 |
| Panzer Tactics (titre provisoire) (CDV) | 1er-nov-06 |
| Pokémon : Donjon Mystère Equipe de Secours Bleue (Nintendo) | 10-nov-06 |
| Mario Slam Basketball (Nintendo) | 10-nov-06 |
| Point Blank (Namco/Bandai/ATARI) | 10-nov-06 |
| Arthur & les Minimoys (ATARI) | 17-nov-06 |
| Souris Story (D3P) | 24-nov-06 |
| Star Fox Command (Nintendo) | 24-nov-06 |
| Totally Spies! 2 Undercover (Namco/Bandai/ATARI) | 24-nov-06 |
| Harlem Globetrotters World Tour (ZOO Digital) | 24-nov-06 |
| Princess Natasha „Student-Secret-Agent-Princess (ZOO Digital) | 24-nov-06 |
| Uno/Skipbo Compilation/Uno Freefall (ZOO Digital) | 24-nov-06 |
| Shrek Smash ‘N Crash Racing (Activision) | déc-06 |
| Touching Detective (Digital Bros) | déc-06 |
| Yoshi’s Island 2 (Nintendo) (titre provisoire) | 1er-déc-06 |
| March of the Penguins (ZOO Digital) | 1er-déc-06 |
| Alex Rider Stormbreaker (THQ) | 4ème trimestre 2006 |
| Guilty Gear (Majesco/THQ) | 4ème trimestre 2006 |
| Rayman contre les Lapins Crétins (Ubisoft) | 4ème trimestre 2006 |
| The Settlers (Ubisoft) | 4ème trimestre 2006 |
| Star Wars Lethal Alliance (Ubisoft) | 4ème trimestre 2006 |
| Charlotte's Web (SEGA) | Hiver 2006 |
Nintendo va sortir un de ses plus grand line-up cette annee, et plus particulièrement cet hiver. Le dernier trimestre 2006 verra la sortie d’une importante variété de nouveaux jeux innovants pour Nintendo DS.